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. 2013 Dec 19;8(12):e82683. doi: 10.1371/journal.pone.0082683

Figure 4. Depletion of neutrophils reverses thrombocytopenia and LPS-induced lung inflammation in F508del mice.

Figure 4

A–B. Under intratracheal LPS challenge, depletion of neutrophils in F508del mice reversed thrombocytopenia (A) and reduced plasma TXB2 levels (B) compared to without neutrophil depletion. C–D. Depletion of neutrophils in F508del mice decreased BAL neutrophils (C) and protein levels (D) compared to without neutrophil depletion. N = 6 in each group. Data were analyzed by t-test and presented in mean ± SD. P values are listed on each panel.