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. 2013 Dec 19;8(12):e82683. doi: 10.1371/journal.pone.0082683

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© 2013 Zhao et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

A. Correction of F508del CFTR trafficking by KM11060 prevented thrombocytopenia. B–D. Rectification of F508del CFTR trafficking by KM11060 reduced BAL neutrophils (B), protein levels (C), and MIP-2 levels (D) in F508del mice under LPS challenge. N = 5 in each group. Data were analyzed by t-test and presented in mean ± SD. P values are listed on each panel.