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. 2013 Dec 19;9(12):e1003386. doi: 10.1371/journal.pcbi.1003386

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© 2013 Halnes et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The set of equations summarizes the electrodiffusive formalism. In equations containing the symbol “±”,“+” should be used for intracellular domain () and “−” should be used for the extracellular domain (). The formalism is general to the choice of membrane mechanisms. , representing system specific membrane mechanisms (ion pumps, ion channels, cotransporters ect.), must to be specified by the user. External input to the system must also be specified. The input must be locally electroneutral, i.e., must fulfill .

Inline graphic — The set of equations summarizes the electrodiffusive formalism. In equations containing the symbol “±”,“+” should be used for intracellular domain () and “−” should be used for the extracellular domain (). The formalism is general to the choice of membrane mechanisms. , representing system specific membrane mechanisms (ion pumps, ion channels, cotransporters ect.), must to be specified by the user. External input to the system must also be specified. The input must be locally electroneutral, i.e., must fulfill .