Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Dec 19;9(12):e1003386. doi: 10.1371/journal.pcbi.1003386

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2013 Halnes et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

(A) Total flux densities into system (). (B) Transmembrane flux densities. (C–F) Longitudinal flux densities due to (C) electrical migration in the ECS, (D) electrical migration in the ICS, (E) diffusion in the ECS and (F) diffusion in the ICS. (A–D) To aid comparison, flux densities were scaled by the relative area fraction (e.g., if , and carry the same the net flux of ion species ). (G) A flow chart that qualitatively summarizes the essential information in (A–F), showing the main transport routes of K⁺ and Na⁺ during SS (Cl⁻ excluded from the overview). K⁺ generally entered the system in the input zone and left the system from some point along the astrocyte axis. The transport route of K+ (from entering to leaving the system) was predominantly intracellular, demonstrating the astrocyte's efficiency as a spatial buffer. Na⁺ entered in the decay zone and left from the input zone. Na⁺ transport predominantly took place in the ECS. The illustration (G) is qualitative - longer arrows mean higher flux densities, but the mapping from (A–F) to (G) is not quantitatively exact. The input zone was in the region . Units on the -axis are in all panels.

Inline graphic — (A) Total flux densities into system (). (B) Transmembrane flux densities. (C–F) Longitudinal flux densities due to (C) electrical migration in the ECS, (D) electrical migration in the ICS, (E) diffusion in the ECS and (F) diffusion in the ICS. (A–D) To aid comparison, flux densities were scaled by the relative area fraction (e.g., if , and carry the same the net flux of ion species ). (G) A flow chart that qualitatively summarizes the essential information in (A–F), showing the main transport routes of K⁺ and Na⁺ during SS (Cl⁻ excluded from the overview). K⁺ generally entered the system in the input zone and left the system from some point along the astrocyte axis. The transport route of K+ (from entering to leaving the system) was predominantly intracellular, demonstrating the astrocyte's efficiency as a spatial buffer. Na⁺ entered in the decay zone and left from the input zone. Na⁺ transport predominantly took place in the ECS. The illustration (G) is qualitative - longer arrows mean higher flux densities, but the mapping from (A–F) to (G) is not quantitatively exact. The input zone was in the region . Units on the -axis are in all panels.