Table 1. Characteristics and frequency of neuronal markers analyzed.

	Antigen recognized by antibody	Expected cellular localizationa	Proposed characteristics of labeled neurons	Data from animal models	% labeled neurons (number of counted neurons (present study))
Ret	GDNF-family ligand receptor tyrosine kinase	Membrane protein, also seen as cytoplasmic and Golgi hn [34]	Small diameter neurons, especially nociceptors [51]	Labels neurons equivalent to KH10 antibody in mouse [23]	26.93 (2306)
TrkA	High-affinity nerve growth factor receptor tyrosine kinase	Cytoplasmic and Golgi hn [52] Plasma membrane ho [53]	Small diameter neurons, especially nociceptors [51]	Labels neurons equivalent to A5 antibody in mouse [23]	61.82 (2499)
nNOS	Neuronal nitric oxide synthase	Cytoplasmic hn [54]	Prevalence in ophthalmic branch of TG [20]	NO can inhibit HSV-1 replication [21]	33.13 (2792)
RT97	Phosphorylated 200kDa neurofilament	Cytoplasmic an [19], [55]	Larger A-type neurons [45]		39.26 (2127)
CGRP	Calcitonin gene-related peptide, a vasodilator and pain mediator	Cytoplasmic hn [56]	Smaller sized neurons [20]	Found throughout the TG of mice [20], and innervate the gingiva in rats [33]	27.16 (2003)
Peripherin	Type III intermediate filament	Cytoplasmic hn [57]	Neurons of the peripheral nervous system and small nerve fibers of the sensory ganglia [58]	Upregulated in response to nerve injury and proinflammatory cytokines [59]	40.87 (2109)

a: References are marked according to whether the experiments were performed in humans (h) or animals (a), and neurons (n) or other cell types (o).