Table 3. Co-localization of neuronal marker proteins using immunofluorescencea,b.
Marker 1 | Marker 2 | Marker 1+/ Marker 2+ | Marker 1+/ Marker 2– | Marker 1–/ Marker 2+ | Marker 1–/ Marker 2– | pc |
Ret | nNOS | 4.5% | 23% | 16.63% | 55.88% | 0.042* |
Ret | CGRP | 15.75% | 19.13% | 16.88% | 48.25% | <0.01* |
TrkA | Ret | 8.38% | 34.75% | 15% | 41.88% | 0.021* |
TrkA | nNOS | 10% | 35.88% | 14.5% | 39.63% | 0.102 |
TrkA | RT97 | 20.13% | 25.25% | 19.63% | 35% | 0.015* |
nNOS | RT97 | 9.25% | 17.75% | 27% | 46% | 0.476 |
a: see Supplementary Table S4 for median and interquartile ranges
b: 800 neurons were counted per marker pair.
c: p-value as calculated by the Pearson Chi-squared test, with p<0.05 taken as significant, shown by an asterisk.