Figure 9. Age-related evolution of brain atrophy in female mice measured through TBM.

Maps of local volumetric change in both female WT (A) and female R6/1 mice (B) between the two time points (9 and 17 weeks of age). Images presented as either global volume change (6 dof) or regional-specific changes corrected for global change (9 dof). Color scales are for volume difference (Volume diff., blue-to-yellow) and the raw t statistical value at each voxel (dark-to-light green). Only volume changes and effects-sizes which survive multiple comparisons corrections across all voxels in the brain (False Discovery Rate with q<0.05) are shown.