. 2013 Dec 19;8(12):e84702. doi: 10.1371/journal.pone.0084702

Table 2. The reliability (Kappa for items 1-11 and ICC for total score) and sensitivity to detect change (MDD) of the NIHSS in an uncontrolled clinical setting.

Item	Physicians vs. Nurses	Nurses vs. Nurses
1a. Level of Consciousness	0.26 (95% CI:0 - 0.54)^*	0.54 (95% CI:0.26 - 0.83)
1b. LOC Questions	0.54 (95% CI:0.28 - 0.79)	0.32 (95% CI:0.04 - 0.59)
1c. LOC Commands	0.74 (95% CI:0.47 - 1.00)	0.65 (95% CI:0.33 - 0.98)
2. Best Gaze	0.08 (95% CI:0 - 0.36)^*	0.45 (95% CI:0.18 - 0.72)
3. Visual	0.43 (95% CI:0.24 - 0.63)	0.39 (95% CI:0.12 - 0.65)
4. Facial Palsy	0.24 (95% CI:0.02 - 0.46)	0.52 (95% CI:0.22 - 0.83)
5a. Motor Arm: Left Arm	0.53 (95% CI:0.30 - 0.76)	0.80 (95% CI:0.58 - 1.00)
5b. Motor Arm: Right Arm	0.39 (95% CI:0.16 - 0.62)	0.62 (95% CI:0.40 - 0.84)
6a. Motor Leg: Left Leg	0.29 (95% CI:0.07 - 0.50)	0.72 (95% CI:0.51 - 0.93)
6b. Motor Leg: Right Leg	0.41 (95% CI:0.16 - 0.65)	0.67 (95% CI:0.43 - 0.91)
7. Limb Ataxia	0^*	0.34 (95% CI:0.08 - 0.60)
8. Sensory	0.17 (95% CI:0 - 0.43)^*	0.35 (95% CI:0.06 - 0.64)
9. Best Language	0.68 (95% CI:0.40 - 0.96)	0.78 (95% CI:0.50 - 1.00)
10. Dysarthria	0.35 (95% CI:0.06 - 0.64)	0.43 (95% CI:0.17 - 0.70)
11. Extinction and Inattention	0.17 (95% CI:0 - 0.46)^*	0.26 (95% CI:0 - 0.55)^*
Total Score	0.78 (95% CI:0.58 - 0.89)	0.75 (95% CI:0.55 - 0.87)
MDD₉₅ of Total Score	± 9.64 Points	± 10.73 Points
MDD₈₀ of Total Score	± 6.31 Points	± 7.02 Points
MDD₇₀ of Total Score	± 5.10 Points	± 5.67 Points
MDD₆₀ of Total Score	± 4.14 Points	± 4.61 Points
MDD₅₀ of Total Score	± 3.32 Points	± 3.69 Points
MDD₄₀ of Total Score	± 2.58 Points	± 2.87 Points
MDD₃₀ of Total Score	± 1.90 Points	± 2.11 Points
MDD₂₀ of Total Score	± 1.25 Points	± 1.39 Points
MDD₁₀ of Total Score	± 0.62 Points	± 0.69 Points

^* Unreliable

MDD subscript is level of confidence (%). Reliability coefficients equal to zero indicate 'unreliable'.