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. 2014 Jan;39(1):6–21. doi: 10.1503/jpn.130009

Table 2.

Summary of changes in anxiety levels occurring after pharmacological activation and genetic inactivation of MT2 receptors

Factor Pharmacological studies with UCM765 Genetic inactivation of MT2 receptors
Elevated plus maze test
 Open arm entries
 Open arm time
Novelty suppressed feeding test
 Latency to eat in a new environment
 Latency to eat in the home cage
Open field test
 Locomotion
 Number of entries in the central area *
 Time spent in the central area *

↑ = increase; ↔ = no change; ↓= decrease.

*

Only during the first 5 minutes of the test session.