Fig. 3.

Risk of recurrence by tumor marker cutoff ratio (TMR) of carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA 19-9), and carbohydrate antigen 72-4 (CA 72-4). (A) CEA shows significant difference in 5-year risk of recurrence between the TMR < 1.0, 1.0 ≤ TMR < 2.0, and 2.0 ≤ TMR groups, with results of 18.3%, 29.8%, 61.4% (P < 0.001). (B) CA 19-9 shows 5-year risk of recurrence of 19.7%, 35.6%, 58.4% between the TMR < 1.0, 1.0 ≤ TMR < 3.0, and 3.0 ≤ TMR groups, respectively with significant difference (P < 0.001). (C) CA 72-4 shows significant difference between the TMR (<1.0) group and groups with TMR higher than 1.0, resulting in of 15.2% and 33.6%, respectively (P < 0.001). NS, nonspecific.