Skip to main content
. 2013 Nov 26;5(11):835–849. doi: 10.18632/aging.100616

Figure 6. Sirt4-AMPK mediated retrograde signaling regulates FAO gene expression.

Figure 6

(A–D) Quantitative RT-PCR of genes involved in fatty acid oxidation (A) PGC1α, (B) ERRα, (C) CPT1b and (D) MCAD from RNA isolated from HEK293T cells transfected with control, Sirt4-FLAG, ANT2-siRNA and Sirt4-FLAG/ANT2-siRNA constructs. Statistical significance was calculated using ANOVA: * p < 0.05, ** p < 0.01, *** p < 0.001 or as indicated. Error bars indicate mean values ± SEM.