Figure 4. Relationship between AGE content in tibial cortical bone and post-yield work-to-fracture in dogs treated with two doses of alendronate (Aln, 0.2 and 1.0 mg kg⁻¹) and two doses of risedronate (0.1 and 0.5 mg kg⁻¹).

Total AGE content was determined by fluorescence reading and using a quinine sulfate as a standard (from Tang et al.48).