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Kinetic parameters of P. falciparum and H. sapiens AsnRSs for tRNA transcript aminoacylation
Results represent averages of at least three independent experiments. nd indicates not detectable.
|
P. falciparum AsnRS |
H. sapiens AsnRS |
|||||
|---|---|---|---|---|---|---|
| Km | kcat | kcat/Km | Km | kcat | kcat/Km | |
| μm | min−1 | min−1 μm−1 10−3 | μm | min−1 | min−1 μm−1 10−3 | |
| tRNAAsn transcripts | ||||||
| P. falciparum WT | 2.0 ± 0.82 | 0.5 ± 0.17 | 252 | nd | nd | nd |
| H. sapiens WT | 6.0 ± 0.28 | 0.2 ± 0.06 | 31 | 2.0 ± 1.12 | 6.7 ± 3.73 | 3350 |
