Table 2. Anti-inflammatory activity of different fractions of methanol extract of T. terrestris.
Treatment | Dose (mg/kg) | Paw edema volume (mL) (3 h after carageenan injection) | Inhibition (%) |
Control (carageenan) | 0.1 mL | 0.68±0.06 | 0.0 |
Cloroform fraction | 200 | 0.19±0.03** | 73.5 |
Aqueous fraction | 200 | 0.75±0.04** | 55.2 |
Ethyl acetate fraction | 200 | 0.65±0.04 | - |
N-butanol fraction | 200 | 0.66±0.03 | - |
Indomethacin | 30 | 0.13±0.02** | 80.8 |
Values represent the mean±SEM, n=6. *: P<0.05. -: not active.