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Overexpression of Mfn2 inhibits proliferation of B lymphoma cell lines BJAB (A, B) and RL (C, D). Overexpression of Mfn2 by adenovirally mediated gene transfer in BJAB cells (A) and RL (C) cells, shown by WB (25 μg cell lysates) with an anti-Mfn2 antibody. β-Tubulin was used as a loading control. Inhibitory effect of Mfn2 on BJAB growth (B) and RL growth (D) was examined by WST-1 assay (n=3, performed in quadruplicate). *P < 0.01.
