Figure 3.

Mfn2 involved in controlling cell proliferation. A) WB of total cell lysates (30 μg) from Mfn2^−/− and WT MEFs probed with an anti-Mfn2 antibody. B) Growth curve of MEFs from WT or Mfn2^−/− mice determined by cell counting (n=3, performed in triplicate). *P < 0.01. C) Level of Mfn2 protein in Mfn2^−/− MEFs infected with either Adv-LacZ or Adv-Mfn2 at 100 pfu/cell. D) Inhibitory effect of Mfn2 on serum-induced Mfn2^−/− MEFs proliferation (n=3, performed in quadruplicate). *P < 0.01.