Figure 1.

Illustration of how applied load affects percent that is absorbed. (a) Three examples of different loads (1, 4, and 10 units) of a given chemical on skin. (b) As long as absorption has not depleted the amount of chemical on the skin too much, flux of the chemical is the same under all conditions. (c) If the experimental duration is such that one load unit penetrates the skin into receptor fluid then on the left, 100% of the load is absorbed; in the middle, the value is 25% and on the right it is 10%.