Fig. 9.
Comparison of Saz-A pretreatment effects on LS-phase function across LSP variants. X. laevis oocytes were injected with unmodified and mutant LSP mRNAs. ACh concentration-response experiments were performed to determine maximal LS-phase function before and after pretreatment with Saz-A (3.16 nM, 5 minutes). The percentage of post-treatment versus pretreatment LS-phase function is displayed for each LSP variant construct used in this study. Values are the mean ± S.E.M. of 6–8 individual determinations collected from three separate experiments. One-way ANOVA showed no significant differences across the LSP variants (F6,14 = 1.85; P = 0.16).