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BRET arrestin affinity and potency values
| Compound | EC50 | Emax |
|---|---|---|
| nM | ||
| Salvinorin A | 5.55 (−8.25 ± 0.05) | 98.84 |
| GR89896 | 0.265 (−9.58 ± 0.03) | 104 |
| ICI 199,441 | 0.461 (−9.34 ± 0.07) | 100 |
| U62066 | 19.8 (−7.70 ± 0.07) | 101 |
| RB 64 | 118 (−6.93 ± 0.06) | 105 |
| RB 48 | 45.0 (−7.35 ± 0.06) | 101 |
| RB 55 | 196 (−6.71 ± 0.03) | 78.9 |
| RB 59 | 3560 (−5.44 ± 0.18) | 177 |
| Dyn 1–13 | 78.2 (−7.11 ± 0.13) | 86.3 |
| Dyn 1–11 | 132 (−6.87 ± 0.16) | 86.9 |
| Dyn 1–9 | 253 (−6.59 ± 0.11) | 92.8 |
| Dyn 1–8 | 1070 (−5.97 ± 0.11) | 102 |
| Dynorphin A | 112 (−6.95 ± 0.13) | 99.2 |
