Figure 2.

Illustration of the predictive performance of the final blood pressure model for sunitinib-treated (left) and placebo-treated (right) patients by prediction-corrected visual predictive checks. Solid circles (•) represent observed diastolic blood pressure, solid lines (—) correspond to the median of the observed blood pressure data, and dashed lines(---) correspond to the 5th and 95th percentiles of the observed data. The shaded areas are the 95% confidence intervals based on the simulated data (n = 500) for the corresponding percentiles.