Schematic overview of signaling pathways involved in catecholamine mediated regulation of angiogenesis in the process of tumor development (a & b). Schematic overview of signaling pathways involved in catecholamine mediated regulation of tumor immunity (c & d) Dopamine (DA), D2 receptors (DAD2), VEGF-A receptor 2 (VEGFR2), MAP kinase (MAPK), focal adhesion kinase (FAK), endothelial cells (EC), endothelial progenitor cells (EPC), matrix metalloproteinase 9 (MMP9), angiopoietin 1 (Ang1), Kruppel like-factor 2 (KLF2), norepinephrine (NE), epinephrine (e), β adrenergic receptors (β AR), α adrenergic receptors (α AR)