Table 3.

IBD-Associated Colorectal Neoplasm Detection Rates by Stool Assay of Methylated DNA Markers

Specificity Cut-off, %	Sensitivity, % (95% CI)
	mBMP3	mVIM	mEYA4	mNDRG4
CRC1
94	89 (51–99)	89 (51–99)	66 (31–91)	44 (15–77)
91	100 (63–100)	89 (51–99)	78 (40–96)	44 (15–77)
89	100 (63–100)	89 (51–99)	100 (63–100)	100 (63–100)
Neoplasia2
94	68 (43–86)	68 (43–86)	53 (29–74)	37 (17–61)
91	84 (60–96)	68 (43–86)	63 (39–82)	37 (17–61)
89	84 (60–96)	68 (43–86)	74 (48–90)	74 (48–90)
Dysplasia
94	50 (20–80)	50 (20–80)	40 (14–73)	30 (8–65)
91	70 (35–91)	50 (20–80)	50 (20–80)	30 (8–65)
89	70 (35–91)	50 (20–80)	50 (20–80)	50 (20–80)

¹CRC = colorectal cancer

²Neoplasia = CRC + premalignant dysplasia combined