FIG. 4.

The patterns of E. coli gene expression after exposure to CORM-3 or iCORM-3 are distinct. The whole-genome expression profiles of E. coli cultures treated with 40 μM CORM-3 (A, C) or iCORM-3 (B, D) are shown over a time course of 2.5, 5, 10, 20, 40, and 80 min. Each line represents a single gene, and those upregulated after 20 min are shown in red; downregulated genes at this time are shown in blue; and genes that do not significantly alter in expression level at 20 min are shown in yellow.