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. 2013 Dec 10;19(17):1999–2012. doi: 10.1089/ars.2012.5103

FIG. 5.

FIG. 5.

Differential transcription factor (TF) activity of cells exposed to CORM-3 versus iCORM-3 under aerobic or anaerobic conditions. (A) TFs identified as having a significantly different activity (p<0.05) after exposure to CORM-3 or iCORM-3. The outer rings of TFs are those that are identified as differentially active under aerobic growth conditions only. The inner circle contains those TFs identified as differentially active under both aerobic and anaerobic conditions. (B) The remaining TFs that were not identified as differentially active under either aerobic or anaerobic growth conditions. (C) Theoretical change in activity of the TF IscR (as generated by TFInfer) in response to CORM-3 (closed circles) and iCORM-3 (open circles) under aerobic (solid lines) or anaerobic (dashed lines) conditions.