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Ciprofloxacin resistance mutations in the gyrA gene
| Strain | Mutation |
|---|---|
| a) MG1655 | Wild type |
| W1-W4 | Ser-83→Leu (TTG) |
| W14 | Tyr-50 (TAC)→Phe (TTT) |
| W23-W26 | Wild type |
| W27 | Tyr-50 (TAC)→Phe (TTT) |
| W28 | Ser-83→deleted |
| W29-W38 | Ser-83→Leu(TTG) |
| W43 | Ala-119 (GCA)→Glu (GAA) |
| W44 | Ser-83→Leu (TTG) |
| W47 | Ser-83→Leu (TTG) |
| W49 | Ser-83→Leu (TTG) |
| b) E. coli ATCC 25922 | Wild type |
| P1 | Wild type |
| P2-P11 | Ser-83→Leu (TTG) |
| P33-P42 | Ser-83→Leu (TTG) |
| P44 | Ser-83→Leu (TTG) |
| P47-P49 | Ser-83→Leu (TTG) |
| P50 | Ser-83→Leu (TTG) |
