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Composision of the cup-core tablet
| Ingredients |
Inner layer (%, w/w)
|
Outer layer
(%, w/w) |
|||
|---|---|---|---|---|---|
| F1 | F2 | F3 | F4 | ||
| Aceclofenac | 25.0 | 25.0 | 25.0 | 25.0 | - |
| Sodium chloride | 69.0 | 59.0 | - | - | - |
| Sodium phosphate | - | - | 69.0 | 59.0 | - |
| Polyvidone K30 | 5.0 | 5.0 | 5.0 | 5.0 | - |
| Magnesium stearate | 1.0 | 1.0 | 1.0 | 1.0 | 3.0 |
| Lactose | - | 10.0 | - | 10.0 | |
| HPMC K4M | - | - | - | - | 50 |
| Carbopol 934P | - | - | - | - | 50 |
