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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: J Mol Cell Cardiol. 2013 Aug 27;64:10.1016/j.yjmcc.2013.08.003. doi: 10.1016/j.yjmcc.2013.08.003

Figure 2.

Figure 2

(A-B) Isoproterenol (ISO)-induced cardiac contractile function in WT and TG mice. LV EF% (A) and heart rate (B) were measured by echocardiogram at baseline and three minutes following intraperitoneal injection of 0.1 mg/kg ISO. Milrinone (Mil, 10mg/kg) was intraperitoneally injected ten minutes before echocardiography. Values are mean ± SEM (n=5 to 13). ** P<0.01 vs. WT. (C-D) Western blotting results showing the levels of phosphorylated-PLB (p-PLB) (C) and phosphorylated-TnI (p-TnI) (D). Band intensities were quantified by densitometry. Fold changes normalized to total PLB or TnI were calculated. Values are mean ± SEM (n=3 each group). *P<0.05 vs. WT.