Table 1.

Effect of intraperitoneal injection of G. glabra var. glandulifera ethanol extract and fractions on clonic seizures induced by pentylenetetrazole in mice

Treatment	Dose	Incidence of clonic seizures (%)
Control 1	10 mL/Kg	100
Control 2	10 mL/Kg	80
Ethosuximide	150 mg/Kg	0٭٭٭
Crude extract	1 g/Kg	80
Crude extract	1.5 g/Kg	60
Crude extract	2 g/Kg	40*
Crude extract	3 g/Kg	30٭٭
Crude extract	4 g/Kg	20٭٭
f1 fraction	1 g/Kg	80
f1 fraction	1.5 g/Kg	30٭٭
f1 fraction	2 g/Kg	20٭٭
f2 fraction	2 g/Kg	70
f2 fraction	4 g/Kg	100
f1A fraction	1 g/Kg	80
f1A fraction	2 g/Kg	80
f1A fraction	3 g/Kg	70
f1B fraction	1 g/Kg	80
f1B fraction	1.5 g/Kg	80

n = 10, ٭: p < 0.05, ٭٭: p < 0.01 and ٭٭٭: p < 0.001 compared to control value. Control 1: Saline, solvent of ethosuximide; Control 2: Tween 80 (25%): DMSO (2 : 1, v/v), solvent of the extract and fractions. f₁: CH₂Cl₂ fraction, f₂: Aqueous fraction, f_1A: n-Hexane fraction, f_1B: Methanol fraction.