Table 1.
Clinical and laboratory findings in patients of metformin or intensive insulin treatment groups before and after treatment
|
Insulin (Protocol A)
|
Metformin (Protocol B)
|
|||
|---|---|---|---|---|
| Day 0 | Day 3 | Day 0 | Day 3 | |
| Age (year) | 45.23 ± 7.14 | 39.47 ± 6.82 | ||
| Mean arterial pressure, mmHg | 89.64 ± 18.9 | 90.41 ± 15.9 | 91.75 ±11.73 | 87.81 ± 16.37 |
| HCO3 | 23.51 ± 2.21 | 21.80 ± 1.5 | 23.81 ± 1.11 | 23.16 ± 2.8 |
| pH | 7.39 ± 0.09 | 7.37 ± 0.08 | 7.38 ± 0.07 | 7.40 ± 0.1 |
| WBC | 6300 ± 320 | 5200 ± 211* | 7600 ± 349 | 5100 ± 226* |
| Sodium (mEq/L) | 149.77 ± 10.3 | 148.27 ± 6.3 | 147.33 ± 12.51 | 145.19 ± 8.66 |
| Potassium (mEq/L) | 3.6 ± 0.84 | 4.12 ± 0.92 | 4.33 ± 1.06 | 4.1 ± 0.88 |
| Blood sugar mg/dL | 152.3 ± 15.32 | 136.7 ± 10.2 | 171.69 ± 28.5 | 131.8 ± 18.0* |
| creatinine mg/dL | 0.72 ± 0.07 | 0.74 ± 0.06 | 0.7 ± 0.07 | 0.72 ± 0.08 |
| GCS | 9.0 ± 3.12 | 10.02 ± 4.63 | 8.47 ± 4.63 | 9.73 ± 5.12 |
| APACHE II | 21.36 ± 5.42 | 21.53 ± 6.1 | 19.11 ± 3.42 | 20.41 ± 3.45 |
All data are presented as Mean ± SEM; * p < 0.05 when compared each variable on day 3 with day 0