Table 2.
Treatment Response and Remission Rates by Patient Subgroup
| Patient Subgroup | Patients, n | Change in PHQ-9 Score, mean (SD) | Responded to Treatment, n (treatment response rate, %) |
Achieved Remission, n (remission rate, %) |
| Overall | 554 | −8.5 (6.3) | 376 (67.9) | 253 (45.7) |
| Gender | ||||
| Female | 424 | −8.7 (6.4) | 287 (67.7) | 189 (44.6) |
| Male | 114 | −8.0 (5.8) | 79 (69.3) | 59 (51.8) |
| Age group, y | ||||
| 18–34 | 79 | −8.6 (5.6) | 50 (63.3) | 39 (49.4) |
| 35–44 | 110 | −8.9 (6.6) | 80 (72.7) | 56 (50.9) |
| 45–54 | 140 | −8.6 (6.2) | 89 (63.6) | 60 (42.9) |
| 55–64 | 141 | −8.4 (6.7) | 100 (70.9) | 60 (42.6) |
| ≥ 65 | 84 | −7.7 (6.1) | 57 (67.9) | 38 (45.2) |
| Monotherapy vs adjuvant therapy | ||||
| Monotherapy | 52 | −7.7 (5.7) | 34 (65.4) | 27 (51.9) |
| Augmentation | 502 | −8.6 (6.3) | 342 (68.1) | 226 (45.0) |
| Duration of depression symptoms | ||||
| ≤ 2 y | 110 | −8.7 (6.4) | 82 (74.5) | 64 (58.2) |
| > 2 y | 427 | −8.7 (6.4) | 282 (66.0) | 179 (41.9) |
| Not sure | 17 | −8.7 (6.4) | 12 (70.6) | 10 (58.8) |
Abbreviation: PHQ-9 = 9-item Patient Health Questionnaire.