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. 2013 Dec 20;11(4):191–195. doi: 10.4321/s1886-36552013000400003

Table 2.

Risk factors associated with Drug-Drug interactions

# Variable Total
No. patients
Patients
with DDI
Adjusted Odds ratio
(95% confidence interval)
P-value
1 All 1510 126    
2 Age        
  60-69 yrs 937 67 1 (reference)  
  70-79 yrs 414 29 0.99 (0.61-1.57) 0.009
  80 yrs or more 159 30 3.04 (1.84-4.94) 0.00
3 Sex        
  Men 943 84 1 (reference)  
  Women 567 42 0.82 (0.55-1.22) 0.30
4 No. of medication        
  Less than 6 340 11 1 (reference)  
  6-10 587 36 1.9 (0.94-4.14) 0.05
  11 or more 583 79 4.5 (2.38-9.47) 0.00
5 Length of stay        
  Less than 10 days 1162 95 1 (reference)  
  10-19 days 309 28 1.13 (0.7-1.78) 0.61
  20 days or more 39 3 1.07 (0.23-3.25) 0.91
6 Num. of Diagnosis        
  Single 292 11 1 (reference)  
  Double 427 38 2.42 (1.2-5.28) 0.007
  Multiple 791 77 2.66 (1.40-5.57) 0.001
Adjusted for confounders like age, sex, number of medications, co-morbid conditions and length of stay