Figure 5. The frequency distribution across model runs for adult females carrying an anti-pathogen gene when adult transgenic mosquitoes are released according to a point-source release pattern.

As in Figure 4, model runs resulting in population extinction are omitted from all panels, and the numbers at the top of each frequency bar represents the proportion of runs resulting in population extinction. The different panels represent release schedules that follow (A) a single year of male-only releases and (B) three years of male-only releases. Releasing more adults consistently raises the variability across model runs. Lines between the frequency bars represent changes in the average frequency of adult females carrying an anti-pathogen gene across runs that do not result in extinction. For extinction frequencies larger than 0.1, the values have been rounded to one decimal place. As in Figure 4, each model run represents a different, randomized spatial configuration of sites. The total release numbers range from approximately 1 to 6.6 million adult mosquitoes for single year releases and from approximately 1 to 9 million adult mosquitoes for three year releases (Table 4). Note these simulations involved higher release numbers per site compared to the case of homogenous releases (Fig. 4); this is necessary to keep the total number of released individuals comparable for both spatial release patterns.