Table 2.
Consistent patients and consistent controls: between-group fMRI results for DD task>SMC trials1
| Brain regions2 | Cluster3 | Voxels4 | x5 | y5 | z5 | t | P6 |
|---|---|---|---|---|---|---|---|
| Controls(task>SMC)>patients(task>SMC) | |||||||
| Frontal cortex – L | 1366 | −48 | 16 | 29 | 3.98 | 0.015 | |
| Inferior frontal gyrus | 289 | ||||||
| Parietal/Occipital cortex – R | 1161 | 30 | −50 | 47 | 4.98 | 0.022 | |
| Inferior parietal gyrus | 428 | ||||||
| Angular gyrus | 132 | ||||||
| Supramarginal gyrus | 52 | ||||||
| Precuneus | 72 | ||||||
| Superior occipital gyrus | 133 | ||||||
| Parietal/Occipital cortex – L | 1651 | −42 | −41 | 48 | 3.70 | 0.007 | |
| Superior parietal gyrus | 234 | ||||||
| Inferior parietal gyrus | 821 | ||||||
| Angular gyrus | 140 | ||||||
| Middle occipital gyrus | 172 | ||||||
| Medial Wall/Dorsal ACC | 1298 | 2 | 18 | 59 | 3.66 | 0.015 | |
| Supplementary motor area – R7 | 538 | ||||||
| Supplementary motor area – L7 | 375 | ||||||
| Middle cingulate gyrus – R | 56 | ||||||
| Middle cingulate gyrus – L | 111 | ||||||
| Thalamus/Basal ganglia | 1627 | 4 | 3 | 0 | 3.60 | 0.007 | |
| Thalamus – L | 255 | ||||||
| Thalamus – R | 247 | ||||||
| Ventral striatum – L | 249 | ||||||
| Pallidum – L | 69 | ||||||
| Midbrain | 360 | ||||||
| Patients(task>SMC)>controls(task>SMC) | |||||||
| Insula/Adjacent cortex – L | 1347 | −12 | −32 | 18 | 4.40 | 0.027 | |
| Insula | 279 | ||||||
| Superior temporal gyrus | 80 | ||||||
| Rolandic operculum | 451 | ||||||
| Postcentral gyrus | 61 | ||||||
| Supramarginal gyrus | 66 | ||||||
| Medial wall | 1556 | −8 | −62 | 48 | 4.04 | 0.022 | |
| Precuneus – R | 602 | ||||||
| Precuneus – L | 646 | ||||||
| Middle cingulate gyrus – R | 172 | ||||||
| Posterior cingulate gyrus – R | 54 | ||||||
Dorsal ACC, dorsal anterior cingulate cortex; L, left; R, right; FDR, false discovery rate; SMC, sensorimotor control.
1
Comparisons for the healthy controls (N = 14) and patients with schizophrenia (N = 14).
2
Identification of activation according to the Wake Forest University (WFU) Pickatlas.
3
Cluster extent.
4
Number of voxels within region identified by WFU Pickatlas; voxel size: 1.5 mm.
5
x, y, and z coordinates in MNI space for most significant voxel within the cluster.
6
FDR-corrected for cluster.
7
Cluster may extend into Presupplementary Motor Area, not recognized by WFU Pickatlas.