Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Jun 11;3(4):431–457. doi: 10.1002/brb3.142

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2013 The Authors. Brain and Behavior published by Wiley Periodicals, Inc.

Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2.5, which does not permit commercial exploitation.

PMC Copyright notice

(A and B) Normal NMJ appearance in the inner TA (types IIa and IIb) and outer TA (primarily type IIb), respectively in P30 animals. Arrows point to normal compact terminal mitochondria. (C) In SOD1 animals, alterations in inner TA, enlarged in a and b, while (D) shows outer TA, enlarged in a'. Asterisks in a and a' are inside of large vacuoles (>100 nm diameter), a common feature in SOD1 animals. Arrows point out swollen mitochondria, and arrowheads point out abnormalities that appear autophagic-like. Double arrows in (E) point to abnormal whorls in a terminal from the outside portion of the TA. Overall, abnormalities of all types were seen 2–3 times more frequently in SOD1 than WT. Representative images are shown. Five animals of each genotype were examined.