Table 2. The activities of glutathione peroxidase, superoxide dismutase, and catalase reduced in the supernatant of the hippocampus and cerebral cortex of rats with AlCl3-induced AD (P<0.05), and the MDA content increased in the supernatant of the hippocampus and cerebral cortex and the erythrocytes of the jugular blood of rats with AlCl3-induced AD.
| Parameters | Control group (n = 10) | (+)Control group (n = 10) | P Value |
| SOD activity in hippo (Inhibition rate/mg) | 18.05%±0.84% | 10.43%±0.99% | <0.01 |
| SOD activity in cortex (Inhibition rate/mg) | 2.84%±0.25% | 1.36%±0.19% | <0.01 |
| Catalase Activity in hippo (mU/ml/mg) | 0.189±0.01 | 0.087±0.009 | <0.01 |
| Catalase Activity in cortex (mU/ml/mg) | 0.050±0.006 | 0.026±0.004 | <0.01 |
| GPx activity in hippo (mU/ml/mg) | 14.52±0.10 | 8.00±0.67 | <0.01 |
| GPx activity in cortex (mU/ml/mg) | 1.18±0.01 | 0.03±0.004 | <0.01 |
| MDA in hippo (nmol/mg) | 0.028±0.005 | 0.117±0.010 | <0.01 |
| MDA in cortex (nmol/mg) | 0.044±0.006 | 0.126±0.010 | <0.01 |
| MDA in RBCs of jugular blood (nmol/mg) | 1.06±0.04 | 3.87±0.12 | <0.01 |
Activities of superoxide dismutase (SOD), catalase, glutathione peroxidase (GPx), and malondialdehyde (MDA) in the control and (+) control groups.
Data are presented as mean ± SD.