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. 2013 Dec 20;8(12):e82667. doi: 10.1371/journal.pone.0082667

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© 2013 Szeto et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A and B) The first 40 random bases of the top 5 UBLCP1 and CHK2 sequences from Cycle 6 in RAPID (top) and SELEX (bottom). Identical sequences between both methods are highlighted with matching colors. The ranks of each sequence at earlier cycles (4, 5 and 6) are also shown. (C) A scatter plot of the 687 common sequences for UBLCP1 in SELEX and RAPID Cycle 6 pools; the dashed line represents a 1∶1 correlation between multiplicities in the two pools. (D) The same analysis for CHK2 yielded 1317 common sequences. On average, RAPID pools were enriched above SELEX pools.