Table 4. The distribution of genotype and allele frequency of MBL2 in the study population.
Polymorphisms | Type 2 diabetes | Controls | P | Type 2 diabetes | P | ||
Normal UAE | Microalbuminuria | Macroalbuminuria | |||||
N | 675 | 855 | – | 260 | 378 | 37 | – |
Rs1800450 | |||||||
GG | 502(74.4) | 588(68.8) | 0.02 | 185(71.2) | 289(76.4) | 28(75.7) | 0.32 |
GA | 155(22.9) | 250(29.2) | 0.01 | 61(23.5) | 64(22.8)* | 8(21.6) | 0.96 |
AA | 18(2.7) | 17(2.0) | 0.38 | 14(5.3) | 3(0.8)* | 1(2.7) | 0.01 |
G | 1159(85.9) | 1426(83.4) | – | 431(82.9) | 664(87.8)* | 64(86.5) | – |
A | 191(14.1) | 284(16.6) | 0.06 | 89(17.1) | 92(12.2) | 10(13.5) | 0.04 |
Rs11003125 | |||||||
GG | 350(51.9) | 411(48.1) | 0.14 | 52(20.0) | 65(17.2) | 5(13.5) | 0.51 |
GC | 122(18.1) | 213(24.9) | 0.01 | 131(50.4) | 198(52.4) | 21(56.8) | 0.73 |
CC | 203(30.0) | 231(27.0) | 0.19 | 77(29.6) | 115(30.4) | 11(29.7) | 0.98 |
G | 822(60.9) | 1035(60.5) | – | 235(45.2) | 328(43.4) | 31(41.9) | – |
C | 528(39.1) | 675(39.5) | 0.84 | 285(54.8) | 428(56.6) | 43(58.1) | 0.76 |
P<0.05 between patients with microalbuminuria and normal UAE.