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. 2013 Dec 20;8(12):e83252. doi: 10.1371/journal.pone.0083252

Table 2. Generated probe sets for melphalan resistance weighted and re-weighted.

Probe ID Gene Symbol Location Weight New Weights
204204_at SLC31A2 9q31-q32 −0.025 −0.507
219748_at TREML2 6p21.1 −0.033 −0.38
203708_at PDE4B 1p31 −0.053 −0.319
201990_s_at CREBL2 12p13 −0.046 −0.314
219049_at CSGALNACT1 8p21.3 −0.037 −0.226
218751_s_at FBXW7 4q31.3 −0.044 −0.184
212055_at C18orf10 18q12.2 0.025 −0.184
205990_s_at WNT5A 3p21-p14 −0.065 −0.077
204786_s_at IFNAR2 21q22.1, 21q22.11 −0.033 −0.0522
217825_s_at UBE2J1 6q15 −0.02 0.0401
201889_at FAM3C 7q31 −0.039 0.074
206405_x_at USP6 17p13 −0.038 0.0888
203895_at PLCB4 20p12 −0.015 0.0982
212122_at RHOQ 2p21 −0.016 0.137
205862_at GREB1 2p25.1 −0.034 0.187
221210_s_at NPL 1q25 0.032 0.189
213555_at RWDD2A 6q14.2 −0.019 0.195
217104_at ST20 15q25.1 0.012 0.201
202043_s_at SMS Xp22.1 0.011 0.486

The first four columns contain a list of probes, genes, location and weights for candidate biomarkers obtained by comparing gene expression data between melphalan sensitive and resistant B cell lines (11). In the fifth column the candidate gene list has undergone an in vivo disease reweighting by PFS in the MRC Myeloma IX training set.