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. 2013 Dec 20;8(12):e83453. doi: 10.1371/journal.pone.0083453

Figure 5. BAL cytokines during chlamydial infection.

Figure 5

Infected adults displayed a more pronounced Th1 cytokine response (IFN-γ and IL-2) than infected neonates (A, B). Infected neonates responded to chlamydial infection with a robust Th2 cytokine response (IL-4, IL-10, IL-5, and IL-13) compared to their adult counterparts (C-F). Specifically, neonatal mice produced significantly elevated levels of IL-4 compared to infected adults 14 and 28 days post infection (P = 0.0312, 0.0248 respectively, D) as well as IL-10 28 days post infection (P = 0.0434 E).