Table 1. Patient Demographics according to utilization of neoadjuvant chemotherapy.
| Value | Initial surgery (N) | Neoadjuvant treatment (N) | Neoadjuvant treatment % | P-value | |
|---|---|---|---|---|---|
| Age | <35 | 22 | 5 | 22.73 | |
| N=2907 | 35-44 | 240 | 21 | 8.75 | |
| 45-54 | 670 | 50 | 7.46 | <0.0001 | |
| 55-64 | 794 | 22 | 2.77 | ||
| 65-74 | 616 | 10 | 1.62 | ||
| >75 | 565 | 3 | 0.53 | ||
| Ethnicity | African American | 60 | 3 | 5.00 | |
| N=2907 | Asian | 72 | 1 | 1.39 | |
| Hispanic | 54 | 2 | 3.70 | 0.3087 | |
| White/ Non-Hispanic | 2287 | 95 | 4.15 | ||
| Other/Unknown | 434 | 10 | 2.30 | ||
| Institution | 1 | 713 | 60 | 8.42 | |
| N=2907 | 2 | 1017 | 11 | 1.08 | <0.0001 |
| 3 | 922 | 23 | 2.49 | ||
| 4 | 255 | 17 | 6.67 | ||
| Preoperative tumor size | 0-10 mm | 646 | 6 | 0.93 | |
| N=2558 | >10-20mm | 1112 | 24 | 2.16 | |
| >20-30mm | 487 | 21 | 4.31 | <0.0001 | |
| >30-40 mm | 177 | 10 | 5.65 | ||
| >40-50 mm | 60 | 9 | 15.00 | ||
| >50 mm | 76 | 12 | 15.79 | ||
| Preoperative diagnosis | IDC | 2439 | 101 | 4.14 | |
| N=2907 | ILC | 282 | 7 | 2.48 | 0.1041 |
| Type Unknown | 186 | 3 | 1.61 | ||
| ER status | Positive | 2423 | 70 | 2.89 | <0.0001 |
| N=2887 | Negative | 464 | 41 | 8.84 | |
| PR status | Positive | 2223 | 62 | 2.79 | <0.0001 |
| N=2887 | Negative | 664 | 49 | 7.38 | |
| Preoperative nodal status | Negative | 2655 | 43 | 1.62 | <0.0001 |
| N=2907 | Positive | 252 | 68 | 26.98 | |
| Initial surgery | Partial mastectomy | 2202 | 60 | 2.72 | <0.0001 |
| N=2907 | Total mastectomy | 705 | 51 | 7.23 |
Abbreviations: BCT, breast conservation therapy; ER, estrogen receptor; PR, progesterone receptor; IDC, invasive ductal carcinoma; ILC, invasive lobular carcinoma