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. 2013 Dec 20;8(12):e84535. doi: 10.1371/journal.pone.0084535

Table 2. Multivariable analysis for association with neoadjuvant chemotherapy use.

Value OR 95% CI P-value
Age <35 6.77 1.33-34.46 0.021
35-44 3.68 1.32-10.29 0.013
45-54 3.92 1.62-9.5 0.003
55-64 2.31 0.90-5.96 0.083
65-74 ref
≥75 0.44 0.11-1.88 0.269
Institution 1 ref
2 0.08 0.03-0.22 <0.0001
3 0.61 0.33-1.10 0.101
4 1.31 0.63-2.75 0.469
Preoperative tumor size 0-10 mm ref
>10-20 mm 1.29 0.50-3.35 0.595
>20-30 mm 1.8 0.67-4.85 0.243
>30-40 mm 2.24 0.72-6.97 0.164
>40-50 mm 6.27 1.77-22.22 0.004
>50 mm 5.69 1.75-18.44 0.004
ER status Positive 0.81 0.36-1.84 0.612
Negative ref
PR status Positive 0.59 0.27-1.28 0.183
Negative ref
Preoperative nodal status Negative ref
Positive 10.17 6.05-17.08 <0.0001
Initial surgery BCT ref
Mastectomy 1.17 0.66-2.08 0.589

Abbreviations: OR, odds ratio; CI, confidence interval; BCT, breast conservation therapy; ER, estrogen receptor; PR, progesterone receptor