Table 2. Multivariable analysis for association with neoadjuvant chemotherapy use.
Value | OR | 95% CI | P-value | |
---|---|---|---|---|
Age | <35 | 6.77 | 1.33-34.46 | 0.021 |
35-44 | 3.68 | 1.32-10.29 | 0.013 | |
45-54 | 3.92 | 1.62-9.5 | 0.003 | |
55-64 | 2.31 | 0.90-5.96 | 0.083 | |
65-74 | ref | |||
≥75 | 0.44 | 0.11-1.88 | 0.269 | |
Institution | 1 | ref | ||
2 | 0.08 | 0.03-0.22 | <0.0001 | |
3 | 0.61 | 0.33-1.10 | 0.101 | |
4 | 1.31 | 0.63-2.75 | 0.469 | |
Preoperative tumor size | 0-10 mm | ref | ||
>10-20 mm | 1.29 | 0.50-3.35 | 0.595 | |
>20-30 mm | 1.8 | 0.67-4.85 | 0.243 | |
>30-40 mm | 2.24 | 0.72-6.97 | 0.164 | |
>40-50 mm | 6.27 | 1.77-22.22 | 0.004 | |
>50 mm | 5.69 | 1.75-18.44 | 0.004 | |
ER status | Positive | 0.81 | 0.36-1.84 | 0.612 |
Negative | ref | |||
PR status | Positive | 0.59 | 0.27-1.28 | 0.183 |
Negative | ref | |||
Preoperative nodal status | Negative | ref | ||
Positive | 10.17 | 6.05-17.08 | <0.0001 | |
Initial surgery | BCT | ref | ||
Mastectomy | 1.17 | 0.66-2.08 | 0.589 |
Abbreviations: OR, odds ratio; CI, confidence interval; BCT, breast conservation therapy; ER, estrogen receptor; PR, progesterone receptor