Table 4.
Evaluation of effect heterogeneity among selected atopic conditions and childhood rhabdomyosarcoma histologic subtypes
| Exposure | Embryonal rhabdomyosarcoma n = 215 |
Alveolar rhabdomyosarcoma n = 66 |
|||
|---|---|---|---|---|---|
| ORa | 95% CI | ORa | 95% CI |
p for heterogeneity |
|
| Allergies | |||||
| No | 1.00 | Ref. | 1.00 | Ref. | |
| Yes | 0.60 | 0.40–0.89 | 0.75 | 0.42–1.35 | 0.53 |
| Hives | |||||
| No | 1.00 | Ref. | 1.00 | Ref. | |
| Yes | 0.66 | 0.40–1.09 | 0.79 | 0.39–1.62 | 0.63 |
| Day-care attendance | |||||
| No | 1.00 | Ref. | 1.00 | Ref. | |
| Yes | 0.64 | 0.45–0.90 | 0.51 | 0.29–0.88 | 0.59 |
| Breastfeeding duration, months | |||||
| 0 | 1.00 | Ref. | 1.00 | Ref. | |
| <6 | 0.90 | 0.58–1.40 | 0.88 | 0.45–1.71 | |
| 6–12 | 0.88 | 0.53–1.47 | 0.63 | 0.26–1.54 | |
| ≥12 | 0.38 | 0.19–0.74 | 0.43 | 0.14–1.31 | 0.65 |
| Number of atopic conditions | |||||
| 0 | 1.00 | Ref. | 1.00 | Ref. | |
| 1 | 1.02 | 0.54–1.90 | 0.92 | 0.39–2.20 | |
| 2 | 0.70 | 0.36–1.35 | 0.80 | 0.32–1.98 | |
| ≥3 | 0.32 | 0.17–0.60 | 0.37 | 0.15–0.95 | 0.90 |
Adjusted for age, race, and sex