Table 1. Mammary tumor incidence rates as a function of radiation dose, for zero dose controls, lead-shielded glands, and unshielded irradiated glands.
| Category | Dose (Gy) | # of dose fractions |
Tumor incidence rate (per 1,000 mouse-days)
|
|
|---|---|---|---|---|
| Rate | 95% CI* | |||
| Zero dose controls | 0 | 1 | 14.2 | 9.4, 20.6 |
| Shielded glands | 0.23 | 1 | 14.2 | 7.7, 24.0 |
| 0.46 | 2 | 12.0 | 6.3, 20.9 | |
| 0.69 | 3 | 22.4 | 14.1, 33.9 | |
| 0.92 | 4 | 22.1 | 13.7, 33.9 | |
| Unshielded irradiated glands | 4 | 1 | 16.5 | 9.4, 27.0 |
| 8 | 2 | 15.3 | 8.7, 25.1 | |
| 12 (PMI dose) | 3 | 10.2 | 4.9, 18.5 | |
| 16 (PMI dose) | 4 | 7.0 | 2.8, 14.5 | |
The last two rows refer to glands irradiated at the doses which were designed to be relevant for PMI (12 and 16 Gy).
* The 95% CIs were estimated using the mid-P approach [30].