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. Author manuscript; available in PMC: 2014 Jan 7.
Published in final edited form as: Cell Transplant. 2013 Jan 16;22(12):10.3727/096368912X662381. doi: 10.3727/096368912X662381

Figure 5.

Figure 5

Histopathological appearance of an area of severe cellular infiltration of remaining non-biopsied islets (at necropsy, in the same recipient pig as in Figure 4) 5 days after islet Tx into the GSMS. (A) Islet mass in the GSMS (H&E, x40). (B) Polymorphonuclear and mononuclear cell infiltrate in islet mass (H&E, x100). (C) Few insulin-positive beta cells were identified whenever severe cell infiltration of the islet mass was present. Islets were infiltrated particularly by (D) CD3+ and (E) CD68+ cells (x200). Similar histopathological findings were detected between biopsied islets (Figure 4) and remaining non-biopsied islets.