Table 1. Comparison of koff (s-1) between groups of sera.
Peptides | Donors/AIH | Donors/SLE | Donors/RA | AIH/SLE | AIH/RA | SLE/RA |
---|---|---|---|---|---|---|
P6 (46-61) | NS | NS | NS | NS | p=0.01 | NS |
P7 (55-70) | p=0.003 | NS | NS | NS | p=0.01 | NS |
P14 (118-133) | NS | p=0.006 | NS | NS | NS | p=0.006 |
P17 (145-160) | NS | NS | p=0.002 | NS | NS | NS |
P20 (172-187) | NS | NS | NS | NS | NS | p=0.004 |
P30 (262-277) | NS | p=0.007 | NS | p=0.004 | NS | NS |
P39 (340-353) | NS | NS | NS | NS | NS | p=0.01 |
The dissociation rate constants koff of sera from the three groups of patients were compared with those of healthy donors, using Kruskal-Wallis test with Dunn-Sidak’s correction (p-value ≤ 0.017). AIH, autoimmune hepatitis. RA, rheumatoid arthritis. SLE, systemic lupus erytematosus. NS, not statistically significant.