. Author manuscript; available in PMC: 2014 Dec 1.

Published in final edited form as: Mol Cancer Res. 2013 Sep 26;11(12):10.1158/1541-7786.MCR-13-0237. doi: 10.1158/1541-7786.MCR-13-0237

Table 1. VRP and RES enhanced UA-mediated cytotoxicity in MT1/2 cells, indicated by a decrease in the IC₅₀ for UA (average of 3-4 independent experiments, n=3/exp).

compound	dose	fold decrease of IC₅₀	p-value
	+veh	1
	+5 μM	1.14±0.16
VRP	+10 μM	1.17±0.19
	+25 μM	1.53±0.31
	+50 μM	1.99±0.41	p<0.01
	+100 μM	2.52±0.53	p<0.05
	+veh	1
	+5 μM	1.00±0.02
CsA	+10 μM	1.03±0.11
	+25 μM	1.13±0.11
	+50 μM	1.25±0.27
	+100 μM	1.24±0.23
	+veh	1
	+5 μM	1.01±0.06
RES	+10 μM	1.01±0.07
	+25 μM	1.38±0.2	p<0.05
	+50 μM	1.35±0.17	p<0.05
	+100 μM	1.3±0.11	p<0.005

Table 1. VRP and RES enhanced UA-mediated cytotoxicity in MT1/2 cells, indicated by a decrease in the IC50 for UA (average of 3-4 independent experiments, n=3/exp).