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. 2013 Dec 20;8(12):e85075. doi: 10.1371/journal.pone.0085075

Figure 2. Chromosome-specific MLH1 values in males and females.

Figure 2

Ten representative large, medium and small chromosomes were identified by FISH and chromosome-specific MLH1 values determined. For all ten chromosomes, mean values were lower in males (white) than females (black), and for nine of the ten the differences were statistically significant: chromosome 1 (10 males, n of cells =139; 7 females, n=83; t=14.1; p<0.0001), 6 (5 males, n=174; 3 females, n=30; t=8.2; p<0.0001), 13 (4 males, n=139; 8 females, n=109; t=8.4; p<0.0001), 14 (4 males, n=142; 4 females, n=70; t=3.2; p<0.005), 15 (6 males, n=130; 3 females, n=45; t=3.3; p<0.005), 16 (12 males, n=204; 9 females, n=63; t=8.8; p<0.0001), 18 (2 males, n=187; 7 females, n=100; t=6.9; p<0.0001), 21 (10 males, n=302; 11 females, n=218; t=7.1; p<0.0001), and 22 (10 males, n=313; 11 females, n=161; t=4.4; p<0.0001). The difference did not reach significance for chromosome 9 (5 males, n=58; 2 females, n=34; t=1.9; p=0.064).