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Defective transforming growth factor beta signalling in CD11c+ cells accelerates atherosclerosis. (A) The plaque area (μm2) in the aortic root of Apoe−/− and Apoe−/−CD11cDNR animals (n = 8, *P < 0.05). (B) The fractional area of the lesion (% stenosis) of Apoe−/− and Apoe−/−CD11cDNR mice (n = 8, *P < 0.05). (C and D) Representative HE staining of atherosclerotic lesions in the aortic root.
