Table 1.
Aptamers | Molecular targets | Associated diseases | Refs | |
---|---|---|---|---|
1 | Macugen | Vascular endothelial growth factor | Age-related macular degeneration | 39 |
2 | AS1411 | Nucleolin | Cancer | 40 |
3 | sgc8 | Protein tyrosine Kinase 7 | Cancer | 41 |
4 | TD05 | Immunoglobulin μ Heavy Chains (IGHM) | Lymphoma | 42 |
5 | A20 | Prostate-specific membrane antigen | Cancer | 43 |
6 | TTA1 | Tenascin C | Cancer | 6 |
7 | S1.3/S2.2 | Mucin 1 | Cancer | 44 |
8 | IGEL1.2 | Immunoglobulin E | Allergy | 45 |
9 | Apt-αvβ3 | αvβ3 integrin | Cancer | 46 |
10 | TBA | α-thrombin | Thrombosis | 8 |
11 | B28 | HIV gp120 | Viral infection | 11 |
12 | NF-κB | Cancer | 47 | |
13 | E2F-E1 | E2F transcription factor | Cancer | 48–49 |
14 | A30 | HER3 | Cancer | 10 |
15 | WT-15 | Plasminogen activator inhibitor 1 | Tumor metastasis | 50 |