Table 1.

Examples of nucleic acid aptamers to targets of therapeutic interest

	Aptamers	Molecular targets	Associated diseases	Refs
1	Macugen	Vascular endothelial growth factor	Age-related macular degeneration	39
2	AS1411	Nucleolin	Cancer	40
3	sgc8	Protein tyrosine Kinase 7	Cancer	41
4	TD05	Immunoglobulin μ Heavy Chains (IGHM)	Lymphoma	42
5	A20	Prostate-specific membrane antigen	Cancer	43
6	TTA1	Tenascin C	Cancer	6
7	S1.3/S2.2	Mucin 1	Cancer	44
8	IGEL1.2	Immunoglobulin E	Allergy	45
9	Apt-αvβ3	αvβ3 integrin	Cancer	46
10	TBA	α-thrombin	Thrombosis	8
11	B28	HIV gp120	Viral infection	11
12		NF-κB	Cancer	47
13	E2F-E1	E2F transcription factor	Cancer	48–49
14	A30	HER3	Cancer	10
15	WT-15	Plasminogen activator inhibitor 1	Tumor metastasis	50